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Sleep and Epidemiology Research Center (SERC)

 

About the SERC

The Case Sleep and Epidemiology Research Center serves as the Polysomnography (PSG) Reading Center for some of the largest National Institutes of Health initiated multi-center studies of sleep disorders. Established in 1994 with the initiation of the Sleep Heart Health Study (SHHS), the SERC has since served as the Reading Center for: the Study of Osteoporetic Fractures in Women Sleep Study; MrOS Sleep Study; Honolulu Asian American Aging Sleep Study, Pickering-NYU Sleep study, and numerous Cleveland-based sleep epidemiological studies. In toto, over the past 10 years, these studies have produced an enormous, unique database of > 14,000 sleep studies, contributing to a database that includes standardized and rigorously collected physiological signals, sleep scoring, and comprehensive clinical and epidemiological information on risk factors, outcomes and co-morbidities. The SERC has developed rigorous methods for training and monitoring technicians and scorers, for conduct of sleep research studies in unattended, community-based settings, and for processing, scoring, analyzing, and archiving thousands of records obtained in diverse settings. (Redline S, Sanders M, Lind B, Quan S, Iber C, Gottlieb D, Bonekat W, Rapoport DW, Smith PL, Kiley J. Methods for obtaining and analyzing unattended polysomnography data for a multicenter study. Sleep NIH 50th Year Commemorative Issue. 1998; 21:759-768.)

Scoring Sleep Studies

We have developed detailed methods for scoring large numbers of PSGs, which include detailed criteria for marking events and dealing with ambiguous tracings.  These approaches have been documented to achieve standardization in scoring PSGs.  Research polysomnologists have undergone rigorous training (with regular ongoing re-training), participate in weekly quality improvement exercises, and are periodically re-evaluated.  Scorer reliability is monitored and tracked.  More...